According to a report by The Hollywood Reporter, Roger Avary (known for Pulp Fiction, Silent Hill, and being stuck Quentin Tarantino's giant foot lovin' shadow)) is set to write and direct the film, with Samuel Hadida and Panorama Media set to produce. We've also got some nice story info for the adaptation as well. According to THR, the upcoming film will center on: 

A young U.S. Army captain and a British special agent on a top-secret mission to Castle Wolfenstein, where Hitler will be for the unveiling of a new secret weapon. After reaching the Castle, the heroes are confronted with Himmler's SS Paranormal Division and must fight, not only for their survival, but for a mission that could alter the course of the war.

Apparently the film will also have the same kind of tone as Inglourious Basterds or Captain America. All of this sounds pretty amazing. There are just not enough Hitler ridiculing films currently, and if the flick is half as fun as the game, then I'm all for it. But if there's no Mecha Hitler...I...I can't predict what I'd do in my blind rage. 

[via THR]